Are There New Mesothelioma Treatments?

Mesothelioma, an uncommon but deadly type of cancer, was diagnosed in over 30,800 people worldwide in 2020. Although there are many known forms of treatment, such as chemotherapy, medical professionals still perform research to determine alternative treatment options. Clinical trials are experimental studies to determine the efficacy and safety of new treatments, prevention methods, and much more. Medical professionals are always looking for a cure for this deadly form of cancer.

Nivolumab and Ipilimumab Trial

This mesothelioma clinical trial for treating patients with rare mesothelioma tumors is in phase II. This particular trial is for mesothelioma patients with rare tumors, such as epithelial tumors or squamous cell carcinomas. According to this trial, immunotherapy drugs for mesothelioma with monoclonal antibodies, such as nivolumab and ipilimumab, might help a patient’s body. They claim that these antibodies assist the body’s ability to attack cancerous cells and interfere with tumor cells’ ability to grow and metastasize.

TAK-500 Clinical Trial

This phase I mesothelioma experimental trial involves three different treatments. The experimental groups will either undergo TAK-500 treatment alone or combined with the Pembrolizumab drug. The FDA approved the Pembrolizumab treatment, a drug to improve the outcome of patients with squamous cell mesothelioma cancer.

SO-C101 in Combination with Keytruda Clinical Trial

This phase I study evaluates the safety and preliminary efficacy of SO-C101 as monotherapy and in combination with Perbrolizumab, or Keytruda, a mesothelioma treatment. This clinical trial is focused on adult patients with metastatic solid or advanced-stage mesothelioma tumors.

Mesothelioma medical professionals are constantly advancing mesothelioma treatment through the power of clinical trials. Connect with a mesothelioma expert today to determine the next steps of your journey.

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Author Madeline May

Madeline works for the patient advocate team and writes about asbestos exposure and mesothelioma. She is passionate about helping families in the mesothelioma community.

Sources

Cancer.Net Editorial Board. (2022, February). Mesothelioma Statistics. Retrieved from Cancer.Net: https://www.cancer.net/cancer-types/mesothelioma/statistics

Memorial Sloan Kettering Cancer Center. (n.d.). A Phase I Study of a Targeted Cancer Vaccine (Galinpepimut-S) Combined with Nivolumab Immunotherapy in Patients with Persistent Pleural Mesothelioma. Retrieved from Memorial Sloan Kettering Cancer Center: https://www.mskcc.org/cancer-care/clinical-trials/17-654

Memorial Sloan Kettering Cancer Center. (n.d.). A Phase I Study of HPN536 in Patients with Advanced Cancers, including Mesothelioma, Pancreatic Cancer, and Ovarian Cancer, that Continue to Grow Despite Standard Therapy . Retrieved from Memorial Sloan Kettering Cancer Center: https://www.mskcc.org/cancer-care/clinical-trials/20-435

National Cancer Institute. (n.d.). Study of SO-C101 and SO-C101 in Combination With Pembro in Adult Patients With Advanced / Metastatic Solid Tumors . Retrieved from National Cancer Institute: https://www.cancer.gov/about-cancer/treatment/clinical-trials/search/v?id=NCI-2020-01336&r=1

With Power. (n.d.). TAK-500 for Squamous Cell Cancer . Retrieved from With Power: https://www.withpower.com/trial/phase-1-triple-negative-breast-neoplasms-10-2021-f8c5b