Medically Reviewed by: Muaiad Kittaneh, MD, FACP, MBA | September 9th, 2019
After a person develops mesothelioma, they may eventually notice symptoms. If this happens, they could go to the doctor’s office for an early screening. The doctor will ask the patient some questions about what they are feeling and decide if more tests are needed. If the doctor continues with testing, they may administer an imaging test. Once this has occurred, if the test is unclear or the doctor sees something that concerns them, they’ll most likely administer a biopsy. This is the most efficient way to test for mesothelioma and get a reliable result. Once they receive the data from a lab, the doctor can diagnose the patient’s condition. This encompasses the doctor’s medical assessment of what illness the patient has and how far along it is.
When symptoms of mesothelioma start to appear, the next logical step for people to take is to visit a hospital or medical center for proper diagnosis. After discussing your symptoms and medical history, your doctor will likely begin with imaging tests, such as X-rays or CT scans, to detect any abnormal growths. If these tests reveal something unusual or the results are unclear, a biopsy will follow. This procedure involves taking a tissue sample to confirm the presence of mesothelioma, making it the most definitive way to diagnose the disease.
Once the biopsy results are in, your doctor will use the information to diagnose the type and stage of mesothelioma, helping guide the next steps for your treatment plan. This is the first stage of a long process when it comes to battling a mesothelioma diagnosis. If any of this sounds overwhelming, you are not alone in that feeling, which is why our contributors have created the following article about diagnosing mesothelioma and how it can shape your treatment options.
Treatment Advocates
Vijayalakshmi Ananthanarayanan, MD
Mesothelioma is a rare and challenging cancer to diagnose, primarily caused by asbestos exposure. With its long latency period—sometimes taking decades to appear—mesothelioma often remains undetected until symptoms, such as chest or abdominal pain and persistent coughing, become noticeable. Given these factors, the diagnostic process can be complex and time-consuming, typically involving multiple tests such as imaging scans, bloodwork, and biopsies.
Because mesothelioma is so rare and takes years to develop, it can take a long time to accurately diagnose the disease, which is usually done with the help of a radiologist. It can be a stressful and time-consuming process. If you show symptoms of mesothelioma, such as chest or abdominal pain or a persistent cough, contact your primary care doctor immediately, especially if you know or suspect that you have encountered asbestos in the past. Due to its aggressive nature, early detection can significantly improve a mesothelioma prognosis.
The most effective diagnosis for mesothelioma involves a combination of blood tests, imaging scans, and biopsies. These tests work together to pinpoint where asbestos exposure has caused damage—most commonly in the lungs, but it can also spread to the heart, abdomen, and testicles. Due to mesothelioma’s long latency period and rarity, it can be difficult to detect early. However, by using multiple diagnostic tools in tandem, doctors can offer a more accurate diagnosis, ensuring that patients receive the right treatment as soon as possible.
The process of diagnosing mesothelioma often begins with imaging tests, which help detect abnormalities in the body. Doctors typically start with basic scans like X-rays and may progress to more detailed imaging, such as CT scans or MRIs, if needed. These tests play a key role in identifying the location and extent of mesothelioma, allowing doctors to determine the best course of action for further diagnosis and treatment.
X-rays are low-resolution, low-radiation images that give doctors a two-dimensional glimpse into the body. Irregularities that may indicate the presence of mesotheliomas, such as fluid buildup, pleural thickening, pleural plaques, tumors, and irregularities in lung size, are usually visible with an X-ray. Abnormal scans may prompt doctors to move on to higher-resolution imaging tests. The average X-ray only takes around 15 minutes.
Computed tomography scans (also referred to as CT or CAT scans) combine rotating X-rays with computers to create multi-angled images of the body. They show if abnormalities are present and give doctors a deeper understanding of the extent and exact location of the abnormality, making them particularly helpful in diagnosing cancer. A CT scan lasts between 10 and 30 minutes, depending on the part of the body.
Positron emission tomography scans, or PET scans, use a small dosage of the radiotracer, a radioactive chemical, to produce three-dimensional images. PET scans can show changes in an organ or tissue at a cellular level, where most diseases begin. This technology allows doctors to determine the stage of mesothelioma based on how far it has spread throughout the patient’s body. Once patients are injected with the radiotracer, it takes about an hour to travel through the body and be absorbed by the affected organs or tissues. The actual scan takes an additional 30 to 60 minutes.
MRIs (magnetic resonance images) use powerful magnetic fields and a computer rather than radiation to create high-resolution, three-dimensional images of affected areas in a patient’s body. They identify areas requiring a biopsy and are often used for staging mesothelioma. MRI test times range from 15 minutes to nearly 60 minutes. Patients with claustrophobia (or a fear of enclosed spaces) may receive anti-anxiety medication, which requires a longer recovery.
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Following imaging tests, blood tests are next in line when diagnosing mesothelioma. The most common blood tests doctors use to diagnose mesothelioma are listed below.
Needle biopsies, often referred to as closed biopsies, are the least invasive option for obtaining tissue samples in the diagnosis of mesothelioma. This outpatient procedure allows patients to undergo the biopsy and return home on the same day. During the process, a thin needle is used to extract small samples of tissue from the affected area, usually guided by imaging techniques such as ultrasound or CT scans. Needle biopsies provide valuable information about the presence of cancerous cells while minimizing recovery time and discomfort, making them a preferred choice for initial diagnostic evaluations in mesothelioma cases.
Camera- or video-assisted biopsies involve a small camera, a computer, and surgical instruments. Generally, a doctor will perform a camera-assisted biopsy after a needle biopsy and before a surgical biopsy.
A surgeon will perform a surgical biopsy when less invasive biopsies fail to provide definitive results. They are conducted under general anesthesia.
After receiving a mesothelioma diagnosis, it’s natural to feel overwhelmed and unsure of what to do next. The first step is finding a doctor with expertise in treating mesothelioma. Specialists in this field understand the complexities of the disease and can guide you through your options, including treatment plans and further testing. Seeking a second opinion is often a good idea, as it provides clarity and confidence in your diagnosis and care. At Mesothelioma Hub, we’re here to connect you with experienced professionals and support you through each step of this journey.
Our team of authors collaborates with the advocate team, focusing on writing about asbestos exposure and mesothelioma to spread awareness. They are dedicated to supporting families within the mesothelioma community.
Dr. Muaiad Kittaneh, MD, FACP, MBA, is a medical oncologist and assistant professor at Loyola University of Chicago. His journey in healthcare includes Internal Medicine training at Advocate Christ Medical Center/University of Illinois of Chicago, where he excelled as Chief Resident. Dr. Kittaneh further honed his expertise at the University of Miami.
Dr. Kittaneh has conducted extensive research and assisted in many clinical trials. His notable contributions have been published in journals across the United States, which focus particularly on breast, melanoma, and gastrointestinal cancers. As an expert medical reviewer, Dr. Kittaneh plays a crucial role in shaping and evaluating Mesothelioma Hub’s content, ensuring accuracy and relevance in the field.
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